Félix d'Herelle’s Followers (3)

Félix d'Herelle

Born

in Montreal, Quebec, Canada

April 25, 1873

Died

February 22, 1949

Website

Genre

카지노싸이트, Biology, Microbiology

Influences

Jacques Monod, James Watson, Sinclair Lewis, Francois Jacob, Andre Lwo ...more

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Félix d'Herelle (April 25, 1873 – February 22, 1949) was a French-Canadian microbiologist, the co-discoverer of bacteriophages (viruses that infect bacteria) and experimented with the possibility of phage therapy. D'Herelle has also been credited for his contributions to the larger concept of applied microbiology.

D'Herelle was born in Montreal, Quebec, the son of French emigrants. His father, 30 years older than Felix's mother, died when Félix was 6 years old. Following his father's death, Félix, his mother and his younger brother Daniel, moved back to Paris. From 7 to 17 years of age, d'Herelle attended school in Paris, including the Lycée Condorcet and Lycée Louis-le-Grand high schools. In the fall of 1891, d'Herelle traveled to Bonn wher Félix d'Herelle (April 25, 1873 – February 22, 1949) was a French-Canadian microbiologist, the co-discoverer of bacteriophages (viruses that infect bacteria) and experimented with the possibility of phage therapy. D'Herelle has also been credited for his contributions to the larger concept of applied microbiology.

D'Herelle was born in Montreal, Quebec, the son of French emigrants. His father, 30 years older than Felix's mother, died when Félix was 6 years old. Following his father's death, Félix, his mother and his younger brother Daniel, moved back to Paris. From 7 to 17 years of age, d'Herelle attended school in Paris, including the Lycée Condorcet and Lycée Louis-le-Grand high schools. In the fall of 1891, d'Herelle traveled to Bonn where he attended lectures at the University of Bonn "for several months." Thus, d'Herelle only obtained a high school education and was self-taught in the sciences. Between 16 and 24, d'Herelle traveled extensively via money given by his mother. When 16 years old, he started to travel through western Europe by bike. When 17, after finishing school, he traveled through South America. Afterwards, he continued his travels through Europe, including Turkey, where he, at 20 years of age, met his wife, Marie Caire.

At age 24, now father of a daughter, d'Herelle and his family moved back to Canada. He built a home laboratory and studied microbiology from books and his own experiments. Through the influence of a friend of his late father, he earned a commission from the Canadian government to study the fermentation and distillation of maple syrup to schnapps. His father's friend shrewdly pointed out that Pasteur "made a good beginning by studying fermentations, so it might be interesting to you, too." He also worked as a medic for a geological expedition, even though he had no medical degree or real experience. Together with his brother, he invested almost all his money in a chocolate factory, which soon went bankrupt.

During this period, d'Herelle published his first scientific paper, "De la formation du carbone par les végétaux" in the May 1901 issue of Le Naturaliste Canadien. The paper is noteworthy for two reasons: it shows an exceptional level of scientific development for a self-taught scientist and reveals a broad level of interest, namely the global balance of carbon in nature. However, the claims of the paper were in error, as d'Herelle contended that the results of his experiments indicated that carbon was a compound, not an element.

D'Herelle became widely known for his imaginative approaches to important problems in theoretical, as well as applied, microbiology. At the same time, he was widely reviled for his self-advertisement, his exaggerated claims of success and his sharp financial practices. He also had a talent for making enemies among powerful senior scientists.

D'Herelle's main legacy lies in the use of phage in the molecular revolution in biology. Max Delbrück and the "phage group" used bacteriophages to make the discoveries that led to the origins of molecular biology. Much of the initial work on the nature of genetic expression and its regulation was performed with bacteriophages by Francois Jacob, Andre Lwoff and Jacques Monod. In fact, immediately before his studies of the structure of DNA, James Watson had earned his Ph.D. by working on a bacteriophage-related project in Salvador Luria's laboratory. A more detailed account of the use of phage in major biological discoveries can be found on the page, bacteriophage.

As one of the earliest applied microbiologists, d'Herelle's microbe-centered worldview has been noted for its prescience, since microbes are playing increasingly important roles in bioremediation, microbial fuel cells, gene therapy, and other areas with relevance to human well-being.

The novel Arrowsmith written by Sinclair Lewis with scientific help from Paul de Kruif was based to a certain extent on the life of d' ...more

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Félix d'Herelle’s books

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	The Bacteriophage, its Rôle in Immunity by Félix d'Herelle, George Hathorn Smith liked it 3.00 avg rating — 1 rating — 26 editions	Error rating book. Refresh and try again. Rate this book Clear rating 1 of 5 stars 2 of 5 stars 3 of 5 stars 4 of 5 stars 5 of 5 stars
	The Bacteriophage and Its Behavior 0.00 avg rating — 0 ratings — 4 editions	Error rating book. Refresh and try again. Rate this book Clear rating 1 of 5 stars 2 of 5 stars 3 of 5 stars 4 of 5 stars 5 of 5 stars
	Felix d'Herelle & the Origins of Molecular Biology 0.00 avg rating — 0 ratings	Error rating book. Refresh and try again. Rate this book Clear rating 1 of 5 stars 2 of 5 stars 3 of 5 stars 4 of 5 stars 5 of 5 stars

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Quotes by Félix d'Herelle (?)

“...on opening the incubator I experienced one of those rare moments of intense emotion which reward the research worker for all his pains: at first glance I saw that the broth culture, which the night before had been very turbid was perfectly clear: all the bacteria had vanished... as for my agar spread it was devoid of all growth and what caused my emotion was that in a flash I understood: what causes my spots was in fact an invisible microbe, a filterable virus, but a virus parasitic on bacteria. Another thought came to me also, If this is true, the same thing will have probably occurred in the sick man. In his intestine, as in my test-tube, the dysentery bacilli will have dissolved away under the action of their parasite. He should now be cured.”
― Felix D'Herelle

tags: bacteria, biology, culture, cure, emotion, experience, incubator, microbes, pain, research, reward, science, true, vaccine, virus

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Félix d'Herelle’s Followers (3)

Félix d'Herelle

Combine EditionsFélix d'Herelle’s books

Combine Editions
Félix d'Herelle’s books